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📌 Brand name: Premarin 💊 Generic name: Conjugated estrogens 62.5 mg/g 📦 Presentation: Vaginal cream, tube with 43 g
🌸 Indications: Premarin is indicated for the treatment of:
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Menopausal symptoms (vaginal dryness, burning, itching)
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Vaginal and vulvar atrophy
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Atrophic vaginitis
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Hormone replacement therapy (HRT)
⚙️ Mechanism of Action: Conjugated estrogens are a mixture of estrogen hormones that bind to estrogen receptors, regulating gene transcription and restoring the vaginal epithelium.
🚫 Contraindications:
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Breast or endometrial cancer
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Active thromboembolic disease
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Undiagnosed vaginal bleeding
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Hypersensitivity to estrogens
⚠️ Precautions:
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Increased risk of thrombosis, especially in predisposed individuals
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Requires medical supervision for long-term use
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Not recommended during pregnancy or breastfeeding
💊 Recommended Dosage:
📦 Storage: Store at room temperature and keep out of reach of children