Bufigen Nalbuphine 10 mg/1ml Amp

$80.42

 

Bufigen Nalbuphine

Nalbuphine belongs to the pharmacological group of opioids, narcotic analgesics, and morphine derivatives. The drug is prescribed for pain of moderate to high intensity. Nalbuphine Hydrochloride does have used in the preoperative and postoperative period with anesthesia during surgery combination. The drug may also be used during childbirth.

Pharmacology

The drug acts at the level of the central nervous system and the brain. It blocks the transmission of pain impulses. The active substance does have characterized by inhibition of conditioned reflexes and sedative action, as well as a less pronounced effect on the respiratory center and the gastrointestinal tract.

If the drug is administered intravenously, the effect appears within a few minutes. When administered intramuscularly, the drug has a slower effect, about 10-15 minutes. The highest concentration is reached after 60-90 minutes. The maximum peak of action of Nalbuphine hydrochloride is reached after 30-60 minutes and lasts for 3-6 hours. Metabolism occurs in the liver. It is administered with the bile as metabolites. If the mother is injected during labor or late gestation, the newborn may have respiratory depression. Excretion occurs partially after 3 to 6 hours.

Nalbuphine Schedule

Nalbuphine hydrochloride is reintroduced after 4-6 hours. If the patient has previously taken morphine or other opioids, Nalbuphine is administered slowly. The dosage is increased gradually. First, administer 25% of the dose and observe the reaction. If side effects do not appear, and withdrawal syndrome does not occur - the remainder of the drug may be administered. Withdrawal syndrome is manifested by gastrointestinal disturbances, allergies, excitability, and anxiety.

Nalbuphine: dosage

Nalbuphine (Nubain) is given intravenously and intramuscularly. The dose is 0.15-0.3 mg/kg of body. The calculation takes into account the patient's condition, the intensity of pain, and other medications the patient is taking. The dose should not be increased by more than 2.4 mg per 1 kg of body weight per day. A single dose of no more than 0.3 mg per 1 kg.

In myocardial infarction, a single dose of 20 mg is administered. Depending on how the acute attack proceeds, 30 mg may be administered. If the condition does not improve, another 20 mg is administered after 30 minutes. If the drug is used in combination with anesthesia, then a larger amount of the drug is taken. For premedication, 100-200 mcg/kg is needed. For anesthesia, 0.3-1 mg/kg is administered intravenously for 10-15 minutes. The maintenance dose of anesthesia is 250-500 mcg/kg intravenously slowly at 30 min intervals. Childbirth is anesthetized with a dose of 20 mg.

Nalbuphine: side effects

Bufigen most often causes adverse reactions related to the nervous system and psyche. A pronounced sedative effect appears. If Nalbuphine (Nubain) is taken uncontrollably and does not follow the dosage, it leads to addiction. After abrupt withdrawal, the body may react with pronounced side effects, so the drug of the opiate group should be used only in hospital conditions or under the supervision of a physician.

Nalbuphine in pregnancy

The drug is contraindicated in pregnancy. If it is used in late pregnancy and during childbirth, the dosage should be no more than 20 mg. You should also monitor the condition of the newborn because the drug can inhibit respiratory function.

Nalbuphine: contraindications

  • Allergy to the active substance or excipients
  • Respiratory and CNS disorders
  • Epilepsy
  • Abdominal surgery until the cause of the acute condition is definitively identified
  • Hepatobiliary surgery
  • Depending on morphine and other drugs containing it
  • Diarrhea that occurs due to pseudomembranous colitis caused by antibiotics
  • Toxic dispersion

Nalbuphine (Nubain) is also contraindicated in patients under 18 years of age.

Our customers can buy Nalbuphine hydrochloride in various forms at the online pharmacy MedicinesMexicoRX. Free shipping is available for bulk purchases. For more information, see the company website or speak to your manager by phone. The drug should not be taken uncontrollably because of the risk of drug addiction and the danger to the patient’s life and health.

Payment & Delivery
Bufigen Nalbuphine 10 mg/1ml Amp
In stock

$80.42

Bufigen Nalbuphine 10 mg/1ml Amp
Tradea Methylphenidate
In stock

$87.12

Choose
Tradea Methylphenidate
Pristiq Desvanlafaxine
In stock

$266.31

Choose
Pristiq Desvanlafaxine
Meticorten prednisone 20 mg 30 Tabs
In stock

$81.03

Meticorten prednisone 20 mg 30 Tabs
Amoxil Amoxicillin Generic 500 mg 12 Caps
In stock

$15.36

Amoxil Amoxicillin Generic 500 mg 12 Caps