Xenical ® is indicated for treatment in conjunction with a hypocaloric diet plan in obese patients or overweight patients, including those risk factors associated with obesity. XENICAL ® provides effective long-term control of weight (reduction, maintenance and prevention of weight gain). XENICAL ® treatment leads to an improvement in risk factors and disorders associated with obesity, including hypercholesterolemia, diabetes mellitus type 2, glucose intolerance, and hypertension heperinsulinemia as well as a reduction in visceral fat. In patients with type 2 diabetes who are overweight (BMI ³ 28 kg/m2) or obese (BMI ≥ 30 kg/m2) XENICAL ®, along with a hypocaloric diet plan, provides additional glycemic control when used in combination with antidiabetic agents such as metformin, sulfonylureas and / or insulin