Valium Diazepam



What is Valium?

Diazepam is a psychotropic drug of the benzodiazepine class with pronounced sedative, anti-anxiety, anticonvulsant, and muscle relaxant effects. The drug also has a hypnotic effect.

The mechanism of action of Valium is related to GABA, which is an inhibitory mediator in the CNS. GABAergic neurons inhibit the activity of other types of neurons. The drug reduces the activity of the GABA transaminase enzyme by increasing the content of GABA in the brain. Inhibition of noradrenergic and dopaminergic neurons is due to the sedative and hypnotic effects of Valium and other benzodiazepines. Anticonvulsant and muscle relaxant effects are due to inhibition of the corresponding neurons of cortical centers and the spinal cord. Inhibition of excitation processes in the reticular ladder system leads to the development of an anxiolytic effect.

Indications for the use of Valium

The drug is prescribed in the following cases:

  • Neurotic disorders, anxiety, which is accompanied by panic attacks

  • For relief of nervous agitation associated with fear and anxiety

  • For epileptic seizures as well as convulsive states of various etiologies

  • Stiffness of the muscle tone (in case of tetanus, acute violations of cerebral circulation)

  • For treating withdrawal syndrome and alcohol abuse delirium

  • During the treatment of hypertension as a result of fear and anxiety, increased excitability, and after stress. In the complex therapy of hypertensive crisis, vasospasm, menopausal and menstrual disorders.

Abrupt termination of taking Valium pills can provoke the occurrence of the ricochet phenomenon, manifested by an aggravation of the condition followed by a rapid reduction of symptoms (change in mood, anxiety or sleep disturbance, restlessness). To prevent ricochet or withdrawal symptoms, a gradual reduction in the dose is recommended.

Valium: side effects

Side effects may occur at the beginning of treatment. The most important side effects include daytime sleepiness and weakness, with impaired alertness and responsiveness.

Other possible side effects of Valium 10 mg: 

  • dizziness, 

  • confusion,

  • impaired gait and movement,

  • headaches and temporary memory lapses, up to and including amnesia.

If the patient has a history of depressive disorders, the drug may exacerbate previously identified symptoms. Sensory disturbances and reversible effects of Valium may also occur.

Prolonged or repeated use of the drug may reduce its effectiveness. Temporary disturbances such as delayed or slurred speech, visual disturbances, and instability in movement and gait may also occur with prolonged use of high doses.

Contraindications to the use of Valium

Valium medication is contraindicated in patients:

  • with hypersensitivity to drugs of the group of benzodiazepines and additional components that are included in the drug; 

  • with a severe form of myasthenia gravis;

  • with severe respiratory insufficiency; 

  • nocturnal apnea syndrome;

  • severe hepatic insufficiency;

  • severe renal insufficiency.

Valium is prescribed with caution in patients with a history of abuse of alcohol or narcotics, strong drugs. Consumption of alcoholic beverages is inadmissible during treatment with Mexican Valium.

Do not use it for drivers of vehicles and people whose activities require quick mental and physical reactions, as well as those connected with a high concentration of attention.

How long does Valium stay in your system?

A long-acting drug used for treating anxiety disorders. It remains in the body for up to 90 days: in urine for up to 6 weeks; in blood for up to 48 hours; in saliva for up to 10 days; in hair for up to 90 days.

After taking Valium 10mg, the effect of the drug is felt from 1 minute to 1 hour, depending on the method of administration.

How long does Valium last?

The half-life of 10 mg Valium is 24-48 hours; in elderly patients, due to decreased hepatic metabolism and clearance, the half-life is 2-4 times longer than in younger patients. 

Valium: dosage

Valium pill is used orally. The dosage of the drug depends on the symptoms of the disease and the age of the patient. Only the attending physician decides how to take Valium. The information is of an informative nature only. Consult your doctor before you buy Valium online.

The standard dosage is 2.5-10 mg 2-3 times a day, the maximum is 60 mg per day.

It is important to choose the correct dosage, starting with the lowest effective dose depending on the pathological condition to be treated.

Treatment should be brief, and the patient should be followed up regularly to see if the therapy should be continued.


Daily dose


Depending on the severity of the symptoms, 2 to 10 mg from 2 to 4 times a day

Alcohol withdrawal

10 mg 3 – 4 times during the first 24 hours, reducing to 5 mg 3 or 4 times daily as needed

For relief of skeletal muscle regurgitation

2 mg-10 mg 3 to 4 times daily


2 mg-10 mg 2 to 4 times daily

Elderly patients or in the presence of debilitating conditions

2 mg to 2.5 mg, 1 to 2 times daily for the first few days; gradually increase the dose as needed and tolerated

Treatment with Valium medication should not exceed 1 month for insomnia and 8-12 weeks for anxiety. Do not stop the drug suddenly.

Valium: generic name

If you want to search and order Valium generic, you must look for the name of the active substance in the drug – Diazepam.

Valium for sleep

Diazepam, the active ingredient in Valium, is a medicine useful in the treatment of insomnia caused by anxiety and stress. The main mechanism of sleeping pills is to inhibit the reticular formation cells of the brainstem.

Valium vs Xanax

The drugs have different active ingredients and dosages in their composition. Although the drugs with similar indications, they are still different drugs.

Let's look at the differences:




Side Effects

Drowsiness, general weakness, dizziness, confusion, impaired or suppressed emotions, double vision and headache.

Gastrointestinal: dry mouth or heavy salivation, heartburn, abdominal pain, nausea, sometimes vomiting, lack of appetite, constipation or diarrhea, liver disorders.

Half-life period

48 hours

From 11 to 13 hours


10 mg tablets 

0.25 mg tablets



The active substance diazepam

The active substance alprazolam

Duration of use

Up to 1 month. More than 4 weeks is not recommended.

From 6 to 8 months

You can buy Valium online in our pharmacy. The price of the drug includes a prescription from a qualified doctor. 

Valium for anxiety

The most striking effect of treatment with benzodiazepines, Valium, in particular, is the anxiolytic effect. In this sense, the drug acts as a sedative, eliminating fears and panic attacks.

Valium for pain

Valium medication is a muscle relaxant and anxiety reliever. Muscle tension, stress, fear, and anxiety can cause headaches, and Valium eliminates the main causes of headaches.

However, the drug should not be taken for long periods of time, as it’s addictive. For those diagnosed with an anxiety disorder, drugs of this group are often prescribed. But headaches can be relieved with less addictive medications such as caffeine, acetaminophen, and aspirin.

Valium withdrawal symptoms

Prolonged use of the drug can lead to psychological and physical dependence. Therefore, when therapy ends, withdrawal symptoms such as sleep disturbances, increased dreaming, anxiety and tension, and internal anxiety may occur.

The dose should be reduced gradually to avoid withdrawal symptoms. The need to increase the dose may be a sign that tolerance to the medication is developing. Once the dose is reduced, the drug should be discontinued.

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